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Maternal complications in diabetic pregnancy

Lookup NU author(s): Dr Gillian Hawthorne


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Pregnant women with diabetes have to manage both the effect of pregnancy on glucose control and its effect on pre-existing diabetic complications. Most women experience hypoglycaemia as a consequence of tightened glycaemic control and this impacts on daily living. Less commonly, diabetic ketoacidosis, a serious metabolic decompensation of diabetic control and a medical emergency, can cause foetal and maternal mortality. Microvascular complications of diabetes include retinopathy and nephropathy. Retinopathy can deteriorate during pregnancy; hence, regular routine examination is required and, if indicated, ophthalmological input. Diabetic nephropathy significantly increases the risk of obstetric complications and impacts on foetal outcomes. Pregnancy outcome is closely related to pre-pregnancy renal function. Diabetic pregnancy is contraindicated if the maternal complications of ischaemic heart disease or diabetic gastropathy are known to be present before pregnancy as there is a significant maternal mortality associated with both of these conditions. (C) 2010 Elsevier Ltd. All rights reserved.

Publication metadata

Author(s): Hawthorne G

Publication type: Article

Publication status: Published

Journal: Best Practice & Research: Clinical Obstetrics & Gynaecology

Year: 2011

Volume: 25

Issue: 1

Pages: 77-90

Print publication date: 04/12/2010

ISSN (print): 1878-156X

ISSN (electronic):

Publisher: Bailliere Tindall


DOI: 10.1016/j.bpobgyn.2010.10.015


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