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A preliminary study of acoustic propagation in thick foam tissue scaffolds composed of poly(lactic-co-glycolic acid)

Lookup NU author(s): Professor Nick ParkerORCiD

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This is the authors' accepted manuscript of an article that has been published in its final definitive form by Institute of Physics Publishing, 2011.

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Abstract

The exclusive ability of acoustic waves to probe the structural, mechanical and fluidic properties of foams may offer novel approaches to characterise the porous scaffolds employed in tissue engineering. Motivated by this we conduct a preliminary investigation into the acoustic properties of a typical biopolymer and the feasibility of acoustic propagation within a foam scaffold thereof. Focussing on poly(lactic-co-glycolic acid), we use a pulse-echo method to determine the longitudinal speed of sound, whose temperature-dependence reveals the glass transition of the polymer. Finally, we demonstrate the first topographic and tomographic acoustic images of polymer foam tissue scaffolds.

Publication metadata

Author(s): Parker NG; Mather ML; Morgan SP; Povey MJW

Publication type: Article

Publication status: Published

Journal: Journal of Physics: Conference Series

Year: 2011

Volume: 269

Issue: 1

Date deposited: 07/03/2012

ISSN (print): 1742-6588

ISSN (electronic): 1742-6596

Publisher: Institute of Physics Publishing

URL: http://dx.doi.org/10.1088/1742-6596/269/1/012019

DOI: 10.1088/1742-6596/269/1/012019

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