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Lookup NU author(s): Professor Heinz Grunze
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Bipolar depression is linked with substantial burden and a high suicide risk, making a rapid and highly efficacious treatment mandatory. However, similar to mania, aspects of long-term treatment should already be considered at treatment initiation. With comparable efficacy, drugs with a beneficial safety and tolerability profile should be preferred. Additional psychotherapy can also noticeably improve both short- and long-term outcome of bipolar depression. Electroconvulsive therapy (ECT) still has its place in severe, treatment-resistant bipolar depression. Whereas ECT is a domain of specialised centres, correct diagnosis and both pharmacological and psychotherapeutic treatment initiation are essential tasks of primary care practitioners and secondary care psychiatrists. © 2010 Springer-Verlag.
Author(s): Grunze H, Dargel S
Publication type: Review
Publication status: Published
Journal: Nervenarzt
Year: 2010
Volume: 81
Issue: 5
Pages: 539-548
Print publication date: 01/05/2010
ISSN (print): 0028-2804
ISSN (electronic): 1433-0407
URL: http://dx.doi.org/10.1007/s00115-009-2851-9
DOI: 10.1007/s00115-009-2851-9
