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Influence of a novel radiopacifier (nano-sized strontia particles) on in vitro properties of a PMMA bone cement for use in total joint replacements

Lookup NU author(s): Dr Matthew GermanORCiD


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In literature reports on strontia-containing PMMA bone cements, the strontia was combined with another material, micron-sized particles were used and in vitro fatigue data are sparse. The present report is on the in vitro characterisation of a strontia-containing PMMA bone cement in which nano-sized strontia particles that were not combined with any other material were used (NANOSRO cement). Compared to the control cement (a commercially-based cement brand with the same composition as that of NANOSRO cement, except that the radiopacifier was BaSO4), NANOSRO cement had significantly higher radiopacity, lower polymerisation rate at 37°C and longer fatigue life. With regard to setting time, maximum exotherm temperature and compressive strength, the values for both cements were within the limits stipulated in the relevant testing standards. These results suggest tha NANOSRO cement has promise for use in anchoring total joint replacement and, therefore, should be studied further. Copyright © 2010 Inderscience Enterprises Ltd.

Publication metadata

Author(s): Lewis G, Towler M, Madigan S, German M

Publication type: Article

Publication status: Published

Journal: International Journal of Nano and Biomaterials

Year: 2010

Volume: 3

Issue: 1

Pages: 78-93

Print publication date: 01/10/2010

ISSN (print): 1752-8933

ISSN (electronic): 1752-8941

Publisher: Inderscience Publishers


DOI: 10.1504/IJNBM.2010.036109


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