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Lookup NU author(s): Dr Charles Kelly,
Professor Vinidh Paleri
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Recurrent, unresectable head and neck squamous cancer is a complex problem. Evidence for the efficacy of treatment is scant in this area and given the large number of patient and tumor variables involved in the recurrent tumor, several factors play a role in deciding the choice of management. The results of treatment are very poor and associated with significant toxicity. Thus, the quality of life outcome following treatment should play a major role in the choice of treatment. Unfortunately, generation of quality-of-life data is hampered by several factors, not least of which are the ethical issues raised by end of life care. This article reviews the relevant literature, summarizes existing evidence and draws conclusions, identifies gaps in the knowledge and offers guidance for further research. © 2010 Expert Reviews Ltd.
Author(s): McLarnon C, Kulloo P, Mehanna H, Kelly C, Paleri V
Publication type: Review
Publication status: Published
Journal: Expert Review of Anticancer Therapy
Print publication date: 01/03/2010
ISSN (print): 1473-7140
ISSN (electronic): 1744-8328
PubMed id: 20214516