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Lookup NU author(s): Maria Morcillo,
Professor Michael North,
Dr Pedro Villuendas
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Ethylene and propylene carbonates are shown to be alternative polar aprotic solvents for cross-aldol reactions catalysed by the primary amino acids (S)-phenylalanine and (S)-tryptophan. In contrast to the corresponding proline-catalysed reactions, both enantiomers of these naturally occurring, primary amino acids are available at low cost. The optimal catalyst and solvent combination needs to be determined on a substrate by substrate basis.
Author(s): Morcillo M, North M, Villuendas P
Publication type: Article
Publication status: Published
Print publication date: 01/06/2011
ISSN (print): 0039-7881
ISSN (electronic): 1437-210X
Publisher: Georg Thieme Verlag
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