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Reversible Hypomagnesaemia-Induced Subacute Cerebellar Syndrome

Lookup NU author(s): Dr Michael Keogh


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Magnesium is the second most abundant intracellular cation and is a fundamental cofactor in a multitude of cellular enzymatic reactions. Magnesium deficiency causes diverse clinical features predominantly due to cardio- and neurotoxicity. We describe a case of severe hypomagnesaemia associated with intermittent downbeat nystagmus, cerebellar ataxia, generalised convulsions and a supraventricular tachycardia. On MRI imaging, a transient lesion of the cerebellar nodulus was observed, which has not, to our knowledge, been previously described in isolated hypomagnesaemia.

Publication metadata

Author(s): Sedehizadeh S, Keogh M, Wills AJ

Publication type: Article

Publication status: Published

Journal: Biological Trace Element Research

Year: 2011

Volume: 142

Issue: 2

Pages: 127-129

Print publication date: 06/07/2010

ISSN (print): 0163-4984

ISSN (electronic): 1559-0720

Publisher: Humana Press, Inc.


DOI: 10.1007/s12011-010-8757-3


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