Browse by author
Lookup NU author(s): Dr Ben Murray, Professor David Fulton
Full text for this publication is not currently held within this repository. Alternative links are provided below where available.
Polymeric nanoparticles were prepared through the chain collapse of linear polymers driven by the formation of dynamic covalent bonds. Linear chains of poly(vinylbenzaldehyde) were intramolecularly cross-linked through the formation of dynamic covalent acylhydrazone bonds with a bis-hydrazide cross-linker. The cross-linking density was shown to be controlled by the amount of crosslinker used. The resulting single polymer chain nanoparticles were then adorned through reaction of their remaining aldehyde units with a series of monoacyl hydrazides or alkoxyamines. Alternatively, the linear polymer chains could be fully adorned by reaction of their aldehyde units with the monoacyl hydrazides and then intramolecularly cross-linked through exchange reactions with the bis-hydrazide cross-linker. Both approaches proved effective routes to prepare single-chain polymer nanoparticles possessing high functional density.
Author(s): Murray BS, Fulton DA
Publication type: Article
Publication status: Published
Journal: Macromolecules
Year: 2011
Volume: 44
Issue: 18
Pages: 7242-7252
Print publication date: 02/09/2011
ISSN (print): 0024-9297
ISSN (electronic): 1520-5835
Publisher: American Chemical Society
URL: http://dx.doi.org/10.1021/ma201331f
DOI: 10.1021/ma201331f
Altmetrics provided by Altmetric