Toggle Main Menu Toggle Search

Open Access padlockePrints

Phylogenetic study of the species within the family Streptomycetaceae

Lookup NU author(s): Professor Michael Goodfellow, Robert Brown, Emeritus Professor Alan Ward


Full text for this publication is not currently held within this repository. Alternative links are provided below where available.


Species of the genus Streptomyces, which constitute the vast majority of taxa within the family Streptomycetaceae, are a predominant component of the microbial population in soils throughout the world and have been the subject of extensive isolation and screening efforts over the years because they are a major source of commercially and medically important secondary metabolites. Taxonomic characterization of Streptomyces strains has been a challenge due to the large number of described species, greater than any other microbial genus, resulting from academic and industrial activities. The methods used for characterization have evolved through several phases over the years from those based largely on morphological observations, to subsequent classifications based on numerical taxonomic analyses of standardized sets of phenotypic characters and, most recently, to the use of molecular phylogenetic analyses of gene sequences. The present phylogenetic study examines almost all described species (615 taxa) within the family Streptomycetaceae based on 16S rRNA gene sequences and illustrates the species diversity within this family, which is observed to contain 130 statistically supported clades, as well as many unsupported and single member clusters. Many of the observed clades are consistent with earlier morphological and numerical taxonomic studies, but it is apparent that insufficient variation is present in the 16S rRNA gene sequence within the species of this family to permit bootstrap-supported resolution of relationships between many of the individual clusters.

Publication metadata

Author(s): Labeda DP, Goodfellow M, Brown R, Ward AC, Lanoot B, Vanncanneyt M, Swings J, Kim SB, Liu Z, Chun J, Tamura T, Oguchi A, Kikuchi T, Kikuchi H, Nishii T, Tsuji K, Yamaguchi Y, Tase A, Takahashi M, Sakane T, Suzuki KI, Hatano K

Publication type: Article

Publication status: Published

Journal: Antonie Van Leeuwenhoek

Year: 2012

Volume: 101

Issue: 1

Pages: 73-104

Print publication date: 01/11/2011

ISSN (print): 0003-6072

Publisher: Springer


DOI: 10.1007/s10482-011-9656-0

PubMed id: 22045019


Altmetrics provided by Altmetric