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GPTIPS: An Open Source Genetic Programming Toolbox For Multigene Symbolic Regression

Lookup NU author(s): Dr Dominic Searson, Professor David Leahy, Dr Mark Willis


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In this contribution GPTIPS, a free, open source MATLAB toolbox for performing symbolic regression by genetic programming (GP) is introduced. GPTIPS is specifically designed to evolve mathematical models of predictor response data that are 'multigene' in nature, i.e. linear combinations of low order non-linear transformations of the input variables. The functionality of GPTIPS is demonstrated by using it to generate an accurate, compact QSAR (quantitative structure activity relationship) model of an existing toxicity data in order to predict the toxicity of chemical compounds. It is shown that the low-order multigene GP methods implemented by GPTIPS can provide a useful alternative, as well as a complementary approach, to currently accepted empirical modelling and data analysis techniques.GPTIPS and documentation is available for download at

Publication metadata

Author(s): Searson DP, Leahy DE, Willis MJ

Editor(s): Ao, S.I., Castillo, O., Douglas, C., Feng, D.D., Lee, J.-A.

Publication type: Conference Proceedings (inc. Abstract)

Publication status: Published

Conference Name: International MultiConference of Engineers and Computer Scientists 2010 (IMECS)

Year of Conference: 2010

Number of Volumes: 3

Pages: 77-80

ISSN: 2078-0958 (print) 2078-0966 (online)

Publisher: Newswood Ltd.


Library holdings: Search Newcastle University Library for this item

Series Title: Lecture Notes in Engineering and Computer Science

ISBN: 9789881701282