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Diagnostic criteria for mild cognitive impairment in Parkinson's disease: Movement Disorder Society Task Force guidelines

Lookup NU author(s): Dr Dag Aarsland, Professor David Burn


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Mild cognitive impairment is common in nondemented Parkinson's disease (PD) patients and may be a harbinger of dementia. In view of its importance, the Movement Disorder Society commissioned a task force to delineate diagnostic criteria for mild cognitive impairment in PD. The proposed diagnostic criteria are based on a literature review and expert consensus. This article provides guidelines to characterize the clinical syndrome and methods for its diagnosis. The criteria will require validation, and possibly refinement, as additional research improves our understanding of the epidemiology, presentation, neurobiology, assessment, and long-term course of this clinical syndrome. These diagnostic criteria will support future research efforts to identify at the earliest stage those PD patients at increased risk of progressive cognitive decline and dementia who may benefit from clinical interventions at a predementia stage. (c) 2012 Movement Disorder Society

Publication metadata

Author(s): Litvan I, Goldman JG, Troster AI, Schmand BA, Weintraub D, Petersen RC, Mollenhauer B, Adler CH, Marder K, Williams-Gray CH, Aarsland D, Kulisevsky J, Rodriguez-Oroz MC, Burn DJ, Barker RA, Emre M

Publication type: Article

Publication status: Published

Journal: Movement Disorders

Year: 2012

Volume: 27

Issue: 3

Pages: 349-356

Print publication date: 24/01/2012

ISSN (print): 0885-3185

ISSN (electronic): 1531-8257

Publisher: John Wiley & Sons, Inc.


DOI: 10.1002/mds.24893


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Funder referenceFunder name
Child Health and Development Institute
Michael J. Fox Foundation for Parkinson's Research
National Parkinson Foundation
Teva Lundbeck
European Union
Parkinson's UK
P50 AG016574National Institutes of Health
NS36630National Institutes of Health
RR024156National Institutes of Health
U01 AG006786National Institutes of Health