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Lookup NU author(s): Dr Ross Harrington,
Emeritus Professor Bill CleggORCiD,
Dr Michael HallORCiD
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The Diels-Alder cycloadducts of 4-vinylimidazoles and N-phenylmaleimide are shown to undergo facile intermolecular ene reactions. Overall the reaction of three simple molecules (a diene, a dienophile and an enophile) in a two-step process gives 4,5,6,7-tetrahydro-1H-benzo[d]imidazoles with high yields, high atom economy and diastereocontrol of up to 5 new stereocentres.
Author(s): Watson LJ, Harrington RW, Clegg W, Hall MJ
Publication type: Article
Publication status: Published
Journal: Organic & Biomolecular Chemistry
Print publication date: 06/07/2012
ISSN (print): 1477-0520
ISSN (electronic): 1477-0539
Publisher: Royal Society of Chemistry
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