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Amantadine-induced myoclonus in a patient with progressive supranuclear palsy

Lookup NU author(s): Professor Alison Yarnall, Professor David Burn


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Progressive supranuclear palsy (PSP) is a tauopathy that generally results in a hypokinetic disorder. Treatment is largely symptomatic, with some small studies indicating a benefit with dopaminergic therapy. Myoclonus is a hyperkinetic disorder that can be seen as part of later stage Parkinson's disease and in multiple system atrophy, but is rarely seen in PSP. Here we report a case of myoclonus precipitated by amantadine in a patient with PSP.

Publication metadata

Author(s): Yarnall AJ, Burn DJ

Publication type: Article

Publication status: Published

Journal: Age and Ageing

Year: 2012

Volume: 41

Issue: 5

Pages: 695-696

Print publication date: 15/03/2012

ISSN (print): 0002-0729

ISSN (electronic): 1468-2834

Publisher: Oxford University Press


DOI: 10.1093/ageing/afs043


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