Toggle Main Menu Toggle Search

Open Access padlockePrints

How can measurement, monitoring, modeling and control advance cell culture in industrial biotechnology?

Lookup NU author(s): Professor Jarka Glassey


Full text for this publication is not currently held within this repository. Alternative links are provided below where available.


This report highlights the potential of measurement, monitoring, modeling and control ((MC)-C-3) methodologies in animal and human cell culture technology. In particular, state-of-the-art of (MC)-C-3 technologies and their industrial relevance of existing technology are addressed. It is a summary of an expert panel discussion between biotechnologists and biochemical engineers with both academic and industrial backgrounds. The latest ascents in (MC)-C-3 are discussed from a cell culture perspective for industrial process development and production needs. The report concludes with a set of recommendations for targeting (MC)-C-3 research toward the industrial interests. These include issues of importance for biotherapeutics production, miniaturization of measurement techniques and modeling methods.

Publication metadata

Author(s): Carrondo MJT, Alves PM, Carinhas N, Glassey J, Hesse F, Merten OW, Micheletti M, Noll T, Oliveira R, Reichl U, Staby A, Teixeira AP, Weichert H, Mandenius CF

Publication type: Article

Publication status: Published

Journal: Biotechnology Journal

Year: 2012

Volume: 7

Issue: 12

Pages: 1522-1529

Print publication date: 05/09/2012

ISSN (print): 1860-6768

ISSN (electronic): 1860-7314

Publisher: Wiley - V C H Verlag GmbH & Co. KGaA


DOI: 10.1002/biot.201200226


Altmetrics provided by Altmetric