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Lookup NU author(s): Professor Jarka Glassey
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This report highlights the potential of measurement, monitoring, modeling and control ((MC)-C-3) methodologies in animal and human cell culture technology. In particular, state-of-the-art of (MC)-C-3 technologies and their industrial relevance of existing technology are addressed. It is a summary of an expert panel discussion between biotechnologists and biochemical engineers with both academic and industrial backgrounds. The latest ascents in (MC)-C-3 are discussed from a cell culture perspective for industrial process development and production needs. The report concludes with a set of recommendations for targeting (MC)-C-3 research toward the industrial interests. These include issues of importance for biotherapeutics production, miniaturization of measurement techniques and modeling methods.
Author(s): Carrondo MJT, Alves PM, Carinhas N, Glassey J, Hesse F, Merten OW, Micheletti M, Noll T, Oliveira R, Reichl U, Staby A, Teixeira AP, Weichert H, Mandenius CF
Publication type: Article
Publication status: Published
Journal: Biotechnology Journal
Year: 2012
Volume: 7
Issue: 12
Pages: 1522-1529
Print publication date: 05/09/2012
ISSN (print): 1860-6768
ISSN (electronic): 1860-7314
Publisher: Wiley - V C H Verlag GmbH & Co. KGaA
URL: http://dx.doi.org/10.1002/biot.201200226
DOI: 10.1002/biot.201200226
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