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Characterization of the ultrasound beam produced by the MIST therapy, wound healing system

Lookup NU author(s): Kim Keltie, Dr Barry Ward, Crispian Oates, Dr Andrew SimsORCiD


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The MIST Therapy wound healing device (Celleration, Eden Prairie, MN, USA), which uses low-frequency ultrasound to deliver an atomized saline spray to acute wounds, was evaluated in a laboratory environment. The output of the MIST device was characterized by its frequency, transmission in the presence and absence of the saline spray and intensity. When measured up to 500 mm away from the transducer tip, the transmission of 39.5 kHz ultrasound was not significantly attenuated by the saline itself. In the absence of the saline spray, the acoustic intensity range of the MIST device was calculated to be 429–188 mW cm−2 across the manufacturer-specified treatment range (12.5–20 mm). Because of the acoustic impedance mismatch between air and soft tissue, the MIST Therapy device would deliver only 0.1% of this incident intensity into the wound site.

Publication metadata

Author(s): Keltie K, Reay CA, Bousfield D, Cole H, Ward B, Oates CP, Sims AJ

Publication type: Article

Publication status: Published

Journal: Ultrasound in Medicine and Biology

Year: 2013

Volume: 39

Issue: 7

Pages: 1233-1240

Print publication date: 01/07/2013

Online publication date: 03/04/2013

Acceptance date: 28/10/2012

ISSN (print): 0301-5629

ISSN (electronic): 1879-291X

Publisher: Elsevier Inc.


DOI: 10.1016/j.ultrasmedbio.2012.10.022

PubMed id: 23562019


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