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Biological functions of natural antisense transcripts

Lookup NU author(s): Dr Andreas Werner



In theory, the human genome is large enough to keep its roughly 20,000 genes well separated. In practice, genes are clustered; even more puzzling, in many cases both DNA strands of a protein coding gene are transcribed. The resulting natural antisense transcripts can be a blessing and curse, as many appreciate, or simply transcriptional trash, as others believe. Widespread evolutionary conservation, as recently demonstrated, is a good indicator for potential biological functions of natural antisense transcripts.

Publication metadata

Author(s): Werner A

Publication type: Editorial

Publication status: Published

Journal: BMC Biology

Year: 2013

Volume: 11

Print publication date: 12/04/2013

ISSN (electronic): 1741-7007

Publisher: BioMed Central Ltd.


DOI: 10.1186/1741-7007-11-31

PubMed id: 23577602

Notes: Article no. 31 is 3 pp.