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Vitamin D supplementation in older people (VDOP): Study protocol for a randomised controlled intervention trial with monthly oral dosing with 12,000 IU, 24,000 IU or 48,000 IU of vitamin D3

Lookup NU author(s): Emeritus Professor Roger Francis, Emerita Professor Elaine McCollORCiD, Dr Thomas Chadwick, Christine Harle, Professor Alison Yarnall, Dr Jennifer Wilkinson, Jennie Parker, Dr Terry AsprayORCiD



The randomised, double blind intervention trial ‘Optimising Vitamin D Status in Older People’ (VDOP) will test the effect of three oral dosages of vitamin D given for one year on bone mineral density (BMD) and biochemical markers of vitamin D metabolism, bone turnover and safety in older people. VDOP is funded by Arthritis Research UK, supported through Newcastle University and MRC Human Nutrition Research and sponsored by the Newcastle upon Tyne Hospitals NHS Foundation Trust.a

Publication metadata

Author(s): Schoenmakers I, Francis RM, McColl E, Chadwick T, Goldberg GR, Harle C, Yarnall A, Wilkinson J, Parker J, Prentice A, Aspray T

Publication type: Article

Publication status: Published

Journal: Trials

Year: 2013

Volume: 14

Print publication date: 17/09/2013

Date deposited: 04/02/2014

ISSN (electronic): 1745-6215

Publisher: BioMed Central Ltd


DOI: 10.1186/1745-6215-14-299


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Funder referenceFunder name
Newcastle University
MP/ID19544Clinical Studies Grant from Arthritis Research UK
U10596037UK MRC