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Lookup NU author(s): Dr Natalie Ferry,
Dr Martin Edwards,
Professor Angharad MR Gatehouse,
Professor Kanglai He
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The full-length cDNA of four Ofapn aminopeptidases were cloned and sequenced from susceptible and resistant Ostrinia furnacalis strains. Four sequences were identified as APN because they shared the common structural features with APN from Lepidoptera, including the signal peptide, GPI anchor signal, the zinc binding/gluzincin motif HEX2HX18E and the gluzincin aminopeptidase motif GAMEN. Compared with APN sequences from the susceptible strain, there were 9, 5, 10 and 12 amino acid variations in the deduced protein sequences from the resistant strain. There were also differences in mRNA expression of the four Ofapn genes between resistant and susceptible O. furnacalis strains. (C) 2013 Published by Elsevier Inc.
Author(s): Xu LN, Wang ZY, Zhang J, Ferry N, Edwards MG, Gatehouse AMR, He KL
Publication type: Article
Publication status: Published
Journal: Journal of Invertebrate Pathology
Print publication date: 21/11/2013
ISSN (print): 0022-2011
ISSN (electronic): 1096-0805
Publisher: Academic Press
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