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Lookup NU author(s): Marcell Wagner,
Professor Alan Bull,
Professor Michael Goodfellow
Full text for this publication is not currently held within this repository. Alternative links are provided below where available.
Dermacoccus abyssi sp. nov. strains MT1.1 and MT1.2 are actinomycetes isolated from a Mariana Trench sediment at a depth of 10 898 m. The fermentation process using complex media led to the production of three new Pigmented heteroaromatic (oxidized and reduced) phenazine compounds, dermacozines H-J (1-3). Extensive use was made of ID and 2D NMR experiments and high-resolution MS to determine the structures of the compounds. The new dermacozines showed radical scavenging activity, and the highest activity was observed for dermacozine H (1), with an IC50 value of 18.8 mu M.
Author(s): Wagner M, Abdel-Mageed WM, Ebel R, Bull AT, Goodfellow M, Fiedler HP, Jaspars M
Publication type: Article
Publication status: Published
Journal: Journal of Natural Products
Print publication date: 05/02/2014
ISSN (print): 0163-3864
ISSN (electronic): 1520-6025
Publisher: American Chemical Society
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