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Looking into the barrel of the RNA exosome

Lookup NU author(s): Dr Claudia SchneiderORCiD


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The exosome complex has key roles in RNA processing and quality control. Single-particle EM analyses now provide compelling evidence for two distinct pathways by which substrate RNAs can pass through the exosome structure to reach the catalytic site for exonuclease digestion.

Publication metadata

Author(s): Schneider C, Tollervey D

Publication type: Editorial

Publication status: Published

Journal: Nature Structural & Molecular Biology

Year: 2014

Volume: 21

Issue: 1

Pages: 17-18

Print publication date: 01/01/2014

Online publication date: 06/01/2014

ISSN (print): 1545-9993

ISSN (electronic): 1545-9985

Publisher: Nature Publishing Group


DOI: 10.1038/nsmb.2750