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Forsterite Nanopowder: Structural Characterization and Biocompatibility Evaluation

Lookup NU author(s): Marieta Naghiu, Dr Elaine Mutch


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Forsterite, a new biocompatible material was synthesized from Mg(lNO(3))(2)center dot 6H(2)O and TEOS by using the sol-gel method. The material was then heated at 800, 900 and 1000 degrees C. The forsterite was noticed as the main crystalline phase in the material fired at 900 and 1000 degrees C, while periclase (MgO) was present in all the samples. The tests confirm that in the first two samples forsterite is present as crystallites <60 nm, while in the sample synthesized at 1000 degrees C it forms aggregates of micrometre-sized grains. In vitro test was performed by immersing the forsterite powder in the simulating body fluids (SBF) and hydroxyapatite formation on the surface was investigated. We could evidence the formation of hydroxyapatite on the forsterite surface after 7 days of immersion. The MTT test confirmed that forsterite powders dissolution promote osteoblast proliferation of the human-type osteoblasts with no significant cytotoxicity effects.

Publication metadata

Author(s): Naghiu MA, Gorea M, Mutch E, Kristaly F, Tomoaia-Cotisel M

Publication type: Article

Publication status: Published

Journal: Journal of Materials Science & Technology

Year: 2013

Volume: 29

Issue: 7

Pages: 628-632

Print publication date: 01/07/2013

Online publication date: 08/04/2013

Acceptance date: 13/02/2013

ISSN (print): 1005-0302

Publisher: Elsevier


DOI: 10.1016/j.jmst.2013.04.007


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Funder referenceFunder name
European Union
Sectoral Operational Programme for Human Resources Development
76841European Social Fund
POSDRU/107/1.5/S/76841European Social Fund
TAMOP-4.2.1.B-10/2/KONV-2010-0001European Social Fund