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Lookup NU author(s): Emeritus Professor Alan MurrayORCiD
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The origin of the T wave shape, the electrocardiographic manifestation of left ventricular repolarisation, is still unclear No explanation has been given for its asymmetrical shape and upright orientation in normal subjects and its tall, symmetrical shape with inverted orientation commonly observed in heart pathologies. In this study a new and simple mathematical model of repolarisation of the left, ventricle and of the associated body potentials is proposed, By choosing three different repolarisation sequences for the left ventricle, T waves with normal orientation rind with pathologically inverted orientation were simulated. Using a normal experimental repolarisation sequence, the T waves in the simulated 12 lead ECG appeared as iii normal subjects. Inverted, tap and symmetrical T waves were obtained using two abnormal repolarisation sequences (inverted epicardial repolarisation, inverted transmural repolarisation) increasing the value of dispersion towards 150 ms, Results from this work strongly suggest that the origin of tall, symmetrically inverted T waves are an increased dispersion of repolarisation in the left ventricle and an abnormal repolarisation sequence.
Author(s): di Bernardo D, Murray A
Publication type: Conference Proceedings (inc. Abstract)
Publication status: Published
Conference Name: PROCEEDINGS OF THE 22ND ANNUAL INTERNATIONAL CONFERENCE OF THE IEEE ENGINEERING IN MEDICINE AND BIOLOGY SOCIETY, VOLS 1-4
Year of Conference: 2000
Pages: 243-246
Publisher: IEEE
Library holdings: Search Newcastle University Library for this item
ISBN: 078036466X
