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Quantification of echo contrast passage across a patent foramen ovale

Lookup NU author(s): Dr Andrew SimsORCiD, David Morris, Emeritus Professor Alan MurrayORCiD


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A patent foramen ovale (PFO) is a potential cardiac source of embolus. Agitated saline is usually injected during transoesophogeal echocardiography (TOE) to detect PFOs by observing contrast passing from right to left atrium. We present a technique far quantifying the level of contrast passing through the septum into the left atrium by analysing captured TOE images. Images were analysed from ten patients with a recent history of stroke and in whom a PFO was found. The technique was sufficiently sensitive to detect a PFO in all cases despite sub-optimal opacification of the right atrium in four of the patients. This study has shown that it is practical to automate the detection and quantification of contrast using image analysis, which we believe is a first step towards a method of objectively quantifying contrast passage across a patent foramen ovale.

Publication metadata

Author(s): Norton MS, Sims AJ, Morris D, Zaglavara T, Kenny MA, Murray A

Publication type: Conference Proceedings (inc. Abstract)

Publication status: Published

Conference Name: Computers in Cardiology 1998

Year of Conference: 1998

Pages: 89-92

Online publication date: 06/08/2002

ISSN: 0276-6547

Publisher: IEEE


DOI: 10.1109/CIC.1998.731730

Library holdings: Search Newcastle University Library for this item

ISBN: 0780352009