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Lookup NU author(s): Dr Clare Burdett,
Dr James Lordan,
Professor John Dark,
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OBJECTIVES: Many centres avoid using cardiopulmonary bypass (CPB) for lung transplant due to concerns over aggravated lung fusion injury and excessive blood loss. We reviewed our 23-years' experience of single lung transplantation.METHODS: A retrospective review of single lung transplants at our institution (1987-2010), examining differences in allograft and postoperative complications between CPB and non-bypass (non-CPB) cases.RESULTS: Two hundred and fifty-nine single lung transplants were undertaken. Fifty-three (20.5%) with CPB. There was no demographically between the two groups. No difference existed in preoperative PO2/FiO(2). At 1 and 24 h, the postoperative ratio was no different (mean 2.95 and 3.24 in non-CPB cases; 3.53 and 3.75 in CPB patients, P=0.18 and P=0.34, respectively). Extubation time was not influenced by the use of CPB. Postoperative blood loss was greater in the CPB group. The usage of frozen plasma and platelets was similar (P = 0.64 and 0.41, respectively). More blood was transfused during postoperative care of patients (P = 0.02).CONCLUSIONS: Fears of poor postoperative lung function after CPB appear unfounded. We could detect no difference in function extubation time. Although the use of CPB increases postoperative bleeding and the need for transfusion, it may be used safely to facilitate lung transplantation.
Author(s): Burdett C, Butt T, Lordan J, Dark JH, Clark SC
Publication type: Article
Publication status: Published
Journal: Interactive Cardiovascular and Thoracic Surgery
Print publication date: 19/06/2012
ISSN (print): 1569-9293
ISSN (electronic): 1569-9285
Publisher: Oxford University Press
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