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A case of metastatic non-neural granular cell tumor in a 13-year-old girl

Lookup NU author(s): Dr Viney Wadehra


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Conventional granular cell tumor represents a mesenchymal neoplasm observed in a variety of locations and is now believed to be of Schwann cell origin. Granular cell change has also been observed in a variety of different tumors, but recently described in the skin has been a distinct entity termed non-neural granular cell tumor, which lacks expression of S100 protein and is of uncertain histogenesis. This tumor typically displays a greater degree of nuclear atypia and mitotic activity than conventional granular cell tumor but appears to behave in a relatively benign fashion, as only two previous instances of lymph node metastasis have been documented. Herein, we report a case of non-neural granular cell tumor arising on the back of a 13-year-old girl, and later axillary lymph node metastasis with extracapsular extension was observed.

Publication metadata

Author(s): Newton P, Schenker M, Wadehra V, Husain A

Publication type: Article

Publication status: Published

Journal: Journal of Cutaneous Pathology

Year: 2014

Volume: 41

Issue: 6

Pages: 536-538

Print publication date: 02/04/2014

ISSN (print): 0303-6987

ISSN (electronic): 1600-0560

Publisher: John Wiley & Sons, Inc.


DOI: 10.1111/cup.12336


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