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Lookup NU author(s): Professor Michael Goodfellow
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A novel angucycline-type antibiotic, warkmycin, was isolated from the culture filtrate of Streptomyces strain Acta 2930. Its chemical structure was elucidated by HR-MS, one-dimensional and 20 NMR experiments. The compound inhibits the growth of Gram-positive bacteria and shows a strong antiproliferative activity against mouse fibroblast cell line NIH-3T3 and human cancer cell lines HepG2 and HT29.
Author(s): Helaly SE, Goodfellow M, Zinecker H, Imhoff JF, Sussmuth RD, Fiedler HP
Publication type: Article
Publication status: Published
Journal: Journal of Antibiotics
Print publication date: 01/11/2013
ISSN (print): 0021-8820
ISSN (electronic): 1881-1469
Publisher: Nature Publishing Group
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