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Analysis of the interaction between the transcription factor σG and the anti-sigma factor SpoIIAB of Bacillus subtilis

Lookup NU author(s): Professor Jeff Errington FRSORCiD


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The activation of sigma(G), a transcription factor, in Bacillus subtilis is coupled to the completion of engulfment during sporulation. SpoIIAB, an anti-sigma factor involved in regulation of sigma(F), is also shown to form a complex with sigma(G) in vitro. SpoIIAA, the corresponding anti-anti-sigma factor, can disrupt the SpoIIAB:sigma(G) complex, releasing free sigma(G). The data suggest the existence of an as-yet-unknown mechanism to keep sigma(G) inactive prior to engulfment.

Publication metadata

Author(s): Evans L, Clarkson J, Yudkin MD, Errington J, Feucht A

Publication type: Article

Publication status: Published

Journal: Journal of Bacteriology

Year: 2003

Volume: 185

Issue: 15

Pages: 4615-4619

ISSN (print): 0021-9193

ISSN (electronic): 1098-5530

Publisher: American Society for Microbiology


DOI: 10.1128/JB.185.15.4615-4619.2003


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