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Electrochemical influence of collagen piezoelectric effect in bone healing

Lookup NU author(s): Dr Ana Ferreira-DuarteORCiD

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Abstract

Bone healing and growth are controlled by the rate of deposition of hidroxiapatite (HA). This process have been so far accredited to the work of osteoblasts, which are attracted by the electrical dipoles produced either by piezoelectricity, due to deformation of the bone, specially the collagen in it, or due to outside electrical stimuli. The present work shows that even without osteoblasts present, the piezoelectric dipoles produced by deformed collagen, can produce the precipitation of HA by electrochemical means, without catalyzer as in biomimetic deposition, These findings could clarify the contribution of osteoblasts in bone growth as compared to the electrochemical action by itself. Further studies ascertaining the osteoblastic activity due to the electric field are being advanced.


Publication metadata

Author(s): Noris-Suárez K, Lira-Olivares J, Ferreira AM, Graterol A, Feijoo JL, Lee SW

Publication type: Conference Proceedings (inc. Abstract)

Publication status: Published

Conference Name: 8th International Symposium on Eco-Materials Processing and Design

Year of Conference: 2007

Pages: 981-984

Publisher: Materials Science Forum

Library holdings: Search Newcastle University Library for this item

Sponsor(s): Engineering and Physical Sciences Research Council (EPSRC),Japan Society for the Promotion of Science (JSPS),Korea Science and Engineering Foundation (KOSEF),JPS-KOSEF Core University Program (CUP),Kyushu Bureau of Economy, Trade and Industry

ISBN: 9780878494316


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