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Controlling competence in Bacillus subtilis: shared use of regulators

Lookup NU author(s): Dr Leendert Hamoen

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Abstract

Bacteria have developed a wide arsenal of survival strategies to cope with the specific problems posed by their environment. These processes are carefully regulated and complex signal transduction cascades ensure proper activation of the adequate adaptive response. An intriguing observation is that generally the regulation pathways of the different adaptive processes are highly intertwined. In this review, this phenomenon is illustrated by the regulation of genetic competence development in Bacillus subtilis. The different regulation pathways which make up the gene regulation network that controls the development of competence are described, and their connections to other adaptive processes in B. subtilis are discussed.

Publication metadata

Author(s): Hamoen LW; Venema G; Kuipers OP

Publication type: Article

Publication status: Published

Journal: Microbiology

Year: 2003

Volume: 149

Issue: 1

Pages: 9-17

ISSN (print): 1350-0872

ISSN (electronic): 1465-2080

Publisher: Society for General Microbiology

URL: http://dx.doi.org/10.1099/mic.0.26003-0

DOI: 10.1099/mic.0.26003-0

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