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Accuracy of three novel predictive methods for measurements of fat mass in healthy older subjects

Lookup NU author(s): Dr Jose Lara-Gallegos, Dr Mario Siervo, Professor John Mathers


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This study evaluated the agreement of novel anthropometric equations and established indirect methods (skinfold thickness and bioimpedance analysis) with reference methods [dual X-ray absorptiometry (DXA) and air displacement plethysmography (ADP)] for fat mass assessment (FM) in older subjects.Methods Forty subjects (M/F = 15/25, age = 61-84 years, BMI = 18-37 kg/m(2)) were recruited. The agreement of the following predictive equations was evaluated: body adiposity index (BAI), BAI-Fels and Clinica Universidad de Navarra-body adiposity estimator (CUN-BAE).Results BAI estimates were comparable to DXA (Delta +/- 2SD = 0.4 +/- 6.0 kg, p > 0.05) but not to ADP (Delta +/- 2SD = -2.8 +/- 7.2 kg, p < 0.001); BAI-Fels estimates were comparable to DXA (Delta +/- 2SD = 0.8 +/- 5.5 kg, p > 0.05) but not to ADP (Delta +/- 2SD = -4.0 +/- 6.9 kg, p < 0.001). The difference between CUN-BAE and ADP was not significant (Delta +/- 2SD = -0.4 +/- 5.6 kg, p[ 0.05), whereas it significantly overestimated DXA (Delta +/- 2SD = 2.8 +/- 5.4 kg, p\ 0.001). ADP significantly overestimated FM compared to DXA (Delta +/- 2SD = 3.2 +/- 5.4 kg, p < 0.001) and the measurement bias was significantly correlated with BMI in men (p = 0.004).Conclusions The accuracy of the three anthropometric indexes is dependent on the choice of the reference method. The variability of the FM estimates was large and these indexes cannot be recommended for the assessment of FM in older subjects.

Publication metadata

Author(s): Lara J, Siervo M, Bertoli S, Mathers JC, Battezzati A, Ferraris C, Tagliabue A

Publication type: Article

Publication status: Published

Journal: Aging Clinical and Experimental Research

Year: 2014

Volume: 26

Issue: 3

Pages: 319-325

Print publication date: 01/06/2014

Online publication date: 10/11/2013

ISSN (print): 1594-0667

ISSN (electronic): 1720-8319

Publisher: Springer


DOI: 10.1007/s40520-013-0169-8


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