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Surgical Management of High Risk Non-Muscle Invasive Bladder Cancer

Lookup NU author(s): Dr Zafer Tandogdu


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High-risk non-muscle invasive bladder cancer(NMIBC) makes up of approximately one third of NMIBC at initial diagnosis and is associated with a significant rate of recurrence, progression and mortality. Due to the ominous nature of high-risk NMIBC thorough evaluation and appropriate management is essential. Quality of the initial resection influences the outcomes. Special attention should be paid to recommendations to improve the quality of resection.New technological developments evaluated seem to be promising in improving the initial management. Until new techniques are proven to improve the outcomes of the initial transurethral resection (TUR), re-staging TUR should be utilized in high-risk disease. A rigorous evaluation of clinical and pathological factors associated with progression should be made. Survival rates after progression are poor and it should be kept in mind that timely performed radical cystectomy, prior to progression to muscleinvasive disease, is associated with excellent oncological outcomes.

Publication metadata

Author(s): Tandogdu Z, Paul-Lerner S

Publication type: Review

Publication status: Published

Journal: Turkiye Klinikleri Journal of Urology-Special Topics

Year: 2014

Volume: 7

Issue: 2

Pages: 72-79

Print publication date: 09/06/2014

ISSN (print): 1308-1101

ISSN (electronic): 2146-8559