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Lookup NU author(s): Dr Zafer Tandogdu
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High-risk non-muscle invasive bladder cancer(NMIBC) makes up of approximately one third of NMIBC at initial diagnosis and is associated with a significant rate of recurrence, progression and mortality. Due to the ominous nature of high-risk NMIBC thorough evaluation and appropriate management is essential. Quality of the initial resection influences the outcomes. Special attention should be paid to recommendations to improve the quality of resection.New technological developments evaluated seem to be promising in improving the initial management. Until new techniques are proven to improve the outcomes of the initial transurethral resection (TUR), re-staging TUR should be utilized in high-risk disease. A rigorous evaluation of clinical and pathological factors associated with progression should be made. Survival rates after progression are poor and it should be kept in mind that timely performed radical cystectomy, prior to progression to muscleinvasive disease, is associated with excellent oncological outcomes.
Author(s): Tandogdu Z, Paul-Lerner S
Publication type: Review
Publication status: Published
Journal: Turkiye Klinikleri Journal of Urology-Special Topics
Year: 2014
Volume: 7
Issue: 2
Pages: 72-79
Print publication date: 09/06/2014
ISSN (print): 1308-1101
ISSN (electronic): 2146-8559
URL: http://www.turkiyeklinikleri.com/article/en-yuksek-risk-kasa-invaze-olmayan-mesane-kanserinde-cerrahi-tedavi-68937.html