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Lookup NU author(s): Dr David Woods
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Fluid retention is a recognized feature of acute mountain sickness. However, accurate assessment of hydration, including the quantification of body water, has traditionally relied on expensive and non-portable equipment limiting its utility in the field setting. We compared the assessment of total body water (TBW) and their relationship to total body weight using two non-invasive methods using the NICas single-frequency bioimpedance analysis (SF-BIA) system and the BodyStat QuadScan 4000 multifrequency BIA system (MF-BIA). TBW measurements were performed at rest at sea level and at high altitude (HA) at 3833 m postexercise and at rest and thereafter at rest at 4450 m and 5129 m on 47 subjects. The average age was 34.5 +/- 9.3 years with an age range of 21-54 years (70.2% male). There were strong correlations between TBW assessment with both methods at sea level (r = 0.90; 95% CI 0.78-0.95: P< 0.0001) and at HA (r = 0.92; 0.8-0.94: P< 0.0001), however, TBW readings were 0.2 l and 1.91 l lower, respectively, with the NICaS. There was a stronger correlation between TBW and body weight with the QuadScan (r = 0.91; P< 0.0001) than with the NICaS (r = 0.83; P< 0.0001). The overall agreement between the two TBW methods was good, but the 95% confidence intervals around these agreements were relatively wide. We conclude that there was reasonable agreement between the two methods of BIA for TBW, but this agreement was lower at HA.
Author(s): Boos CJ, Holdsworth DA, Hall DP, Mellor A, O'Hara J, Woods DR
Publication type: Article
Publication status: Published
Journal: Clinical Physiology and Functional Imaging
Year: 2014
Volume: 34
Issue: 6
Pages: 478-484
Print publication date: 01/11/2014
Online publication date: 04/05/2014
Acceptance date: 02/12/2013
ISSN (print): 1475-0961
ISSN (electronic): 1475-097X
Publisher: Wiley-Blackwell
URL: http://dx.doi.org/10.1111/cpf.12121
DOI: 10.1111/cpf.12121
PubMed id: 24797153
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