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Lookup NU author(s): Dr Ulrich Baisch, Dr Liana Vella-Zarb
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A detailed structural study and Hirshfeld surface analysis of cabazitaxel in its anhydrous, hydrated and solvated forms have revealed that the three-dimensional architecture of the drug molecule is retained regardless of the crystalline environment. This prompted comparison with its taxane predecessors, suggesting key factors contributing to cabazitaxel's poor affinity to P-gp.
Author(s): Baisch U, Vella-Zarb L
Publication type: Article
Publication status: Published
Journal: CrystEngComm
Year: 2014
Volume: 16
Issue: 44
Pages: 10161-10164
Print publication date: 28/11/2014
Online publication date: 01/08/2014
Acceptance date: 01/08/2014
ISSN (print): 1466-8033
Publisher: ROYAL SOC CHEMISTRY
URL: http://dx.doi.org/10.1039/C4CE01279H
DOI: 10.1039/c4ce01279h
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