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Lookup NU author(s): Professor Bloss Stephan
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Accurate detection of individuals with cognitive impairment and dementia in addition to identification of those at high risk of future disease is important to guide clinical care, and has research implications regarding clinical trial recruitment and development of dementia preventative strategies. In this narrative review, we describe new proposed criteria for early diagnosis of Alzheimer's disease (AD). We also explore risk factors for dementia and evaluate methods for screening for increased risk of incident disease. We highlight variability in different diagnostic approaches. Additional work needs to be done to validate new methods across different settings (such as population-based, primary care, and memory clinics), age, and ethnic groups. Having an accurate method to assess for dementia and predict risk in routine clinical care will aid decision making and could ultimately lead to disease prevention.
Author(s): Stephan BCM, Brayne C
Publication type: Review
Publication status: Published
Journal: Journal of Alzheimer's Disease
Year: 2014
Volume: 42
Issue: Supp 4
Pages: S329-S338
Print publication date: 01/01/2014
Online publication date: 26/09/2014
Acceptance date: 16/09/2014
ISSN (print): 1387-2877
ISSN (electronic): 1875-8908
Publisher: IOS PRESS
URL: http://dx.doi.org/10.3233/JAD-141413
DOI: 10.3233/JAD-141413
