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Lookup NU author(s): Professor Patrick DegenaarORCiD, Dr Rolando Berlinguer PalminiORCiD
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Here we demonstrate the use of a micro-Light Emitting Diode Arrays as a powerful tool for complex spatiotemporal control of photosensitized neurons. The array can generate arbitrary, 2D, excitation patterns with millisecond and micrometer resolution. In particular, we describe an active matrix control address system to allow simultaneous control of 256 individual micro light emitting diodes. We present the system optically integrated into a microscope environment and patch clamp electrophysiology. The results show that the emitters have sufficient radiance at the required wavelength to stimulate neurons expressing channelrhodopsin-2 (ChR2)
Author(s): Degenaar P, McGovern B, Berlinguer-Palmini R, Vysokov N, Grossman N, Pohrer V, Drakakis E, Neil M
Publication type: Conference Proceedings (inc. Abstract)
Publication status: Published
Conference Name: IEEE Biomedical Circuits and Systems Conference (BioCAS 2010)
Year of Conference: 2010
Online publication date: 04/02/2011
Acceptance date: 05/11/2010
ISSN: 2163-4025
Publisher: IEEE
URL: https://doi.org/10.1109/BIOCAS.2010.5709598
DOI: 10.1109/BIOCAS.2010.5709598
Library holdings: Search Newcastle University Library for this item
ISBN: 9781424472703
