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The role of endocrine insulin-like growth factor-I (IGF-I) in female bovine reproduction

Lookup NU author(s): Dr Miguel Velazquez


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Insulin-like growth factor-I (IGF-I) plays a pivotal role in cattle fertility, acting as a monitoring signal that allows reproductive events to occur when nutritional conditions for successful reproduction are reached. However, endocrine IGF-I is not a predictor of reproductive events, but rather an indirect estimator of the suitability of the animal to achieve the reproductive event in question. Although measuring circulating IGF-I concentrations might not have any clinical application in the cattle industry, endocrine IGF-I screening will continue to be important for the study of interactions between nutrition and reproduction. In addition, endocrine IGF-I screening could be used as an ancillary test for the selection of cattle for high reproductive potential, especially in herds of high genetic merit for milk production, in which a decline in fertility has been identified.

Publication metadata

Author(s): Velazquez MA, Spicer LJ, Wathes DC

Publication type: Review

Publication status: Published

Journal: Domestic Animal Endocrinology

Year: 2008

Volume: 35

Issue: 4

Pages: 325-342

Print publication date: 01/11/2008

Online publication date: 08/08/2008

Acceptance date: 14/07/2008

ISSN (print): 0739-7240

ISSN (electronic): 1879-0054

Publisher: Elsevier


DOI: 10.1016/j.domaniend.2008.07.002