Browse by author
Lookup NU author(s): Dr Harold Fellermann,
Professor Natalio KrasnogorORCiD
Full text for this publication is not currently held within this repository. Alternative links are provided below where available.
Biological systems employ compartmentalisation in order to orchestrate a multitude of biochemical processes by simultaneously enabling “data hiding” and modularisation. In this paper, we present recent research projects that embrace compartmentalisation as an organisational programmatic principle in synthetic biological and biomimetic systems. In these systems, artificial vesicles and synthetic minimal cells are envisioned as nanoscale reactors for programmable biochemical synthesis and as chassis for molecular information processing. We present P systems, brane calculi, and the recently developed chemtainer calculus as formal frameworks providing data hiding and modularisation and thus enabling the representation of highly complicated hierarchically organised compartmentalised reaction systems. We demonstrate how compartmentalisation can greatly reduce the complexity required to implement computational functionality, and how addressable compartments permit the scaling-up of programmable chemical synthesis.
Author(s): Fellermann H, Krasnogor N
Publication type: Article
Publication status: Published
Journal: Lecture Notes in Computer Science
Altmetrics provided by Altmetric