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Mitochondrial Causes of Epilepsy: Evaluation, Diagnosis, and Treatment

Lookup NU author(s): Dr Hannah Steele, Professor Patrick Chinnery


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Mitochondrial disorders are frequently associated with seizures. In this review, the authors discuss the seizure patterns and distinguishing features of mitochondrial epilepsy, alongside the indications for investigating, and how to investigate epilepsy from a mitochondrial perspective. Finally, they discuss management strategies for this complex group of patients.

Publication metadata

Author(s): Steele HE, Chinnery PF

Publication type: Article

Publication status: Published

Journal: Seminars in Neurology

Year: 2015

Volume: 35

Issue: 3

Pages: 300-309

Print publication date: 01/06/2015

ISSN (print): 0271-8235

ISSN (electronic): 1098-9021

Publisher: Georg Thieme Verlag KG


DOI: 10.1055/s-0035-1552624


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Funder referenceFunder name
National Institute for Health Research (NIHR) Newcastle Biomedical Research Centre based at Newcastle upon Tyne Hospitals NHS Foundation Trust and Newcastle University
096919Z/11/ZWellcome Trust Centre for Mitochondrial Research
G0601943Medical Research Council (UK) Centre for Translational Muscle Disease research