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Rose Bengal incorporated in mesostructured silica nanoparticles: structural characterization, theoretical modeling and singlet oxygen delivery

Lookup NU author(s): Dr Fabio Cucinotta

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Abstract

Rose Bengal (RB), a xanthene dye, incorporated into mesostructured silica nanoparticles (MSNs) exhibits efficient singlet oxygen (O-1(2)) generation when illuminated with 540 nm green light which is particularly promising for PDT applications. Several systems with different RB loadings were synthesized and fully characterized by means of spectroscopic techniques in combination with a computational study, to optimize the amount of RB in order to avoid the formation of aggregates that is detrimental for a high O-1(2) delivery.

Publication metadata

Author(s): Estevao BM, Cucinotta F, Hioka N, Cossi M, Argeri M, Paul G, Marchese L, Gianotti E

Publication type: Article

Publication status: Published

Journal: Physical Chemistry Chemical Physics

Year: 2015

Volume: 17

Issue: 40

Pages: 26804-26812

Print publication date: 28/10/2015

Online publication date: 09/09/2015

Acceptance date: 08/09/2015

ISSN (print): 1463-9076

ISSN (electronic): 1463-9084

Publisher: Royal Society of Chemistry

URL: http://dx.doi.org/10.1039/c5cp03564c

DOI: 10.1039/c5cp03564c

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