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Impact of age on access site-related outcomes in 469,983 percutaneous coronary intervention procedures: Insights from the British Cardiovascular Intervention Society

Lookup NU author(s): Professor Bernard Keavney, Professor Azfar Zaman, Dr Mark De Belder


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We investigate adoption of the TRA in different age groups and study the relationship between age and access site related outcomes in a national cohort of patients undergoing PCI in the UK. Previous studies have reported conflicting data on radial access site adoption between different age groups, with age an independent predictor of failure of procedures undertaken through the radial approach. Age and access site related outcomes (based on transradial (TRA) and transfemoral (TFA) access) were studied in 469,983 PCI procedures undertaken in the UK from 2006 to 2012 in the age groups; <60, 60-<70, 70-<80, and 80 in the British Cardiovascular Intervention Society database. We studied access site practice in 469,983 patients who underwent PCI procedures in the United Kingdom. TRA utilization increased from 17.5% to 65.6% in the age group <60, and 16.6% to 54.5% in the age group 80 between 2006 and 2012. TRA was independently associated with decreased 30-day mortality in all age groups (<60: OR 0.64; 95% CI 0.54-0.74, P<0.0001; 60-<70: OR 0.65; 95% CI 0.57-75, P<0.0001, 70-<80: OR 0.58 (0.52-0.65, P<0.0001 and 80: OR 0.65 (0.57-0.73, P<0.0001). Adoption of the TRA for PCI has occurred least in older patients in the UK despite similar associations between TRA use and decreased 30-day mortality observed in all age groups. (c) 2015 Wiley Periodicals, Inc.

Publication metadata

Author(s): Anderson SG, Ratib K, Myint PK, Keavney B, Kwok CS, Zaman A, Ludman PF, de Belder MA, Nolan J, Mamas MA, Natl Inst Cardiovasc Outcomes Res, British Cardiovasc Intervention S

Publication type: Article

Publication status: Published

Journal: Catheterization Cardiovascular Interventions

Year: 2015

Volume: 86

Issue: 6

Pages: 965-972

Print publication date: 15/11/2015

Online publication date: 25/02/2015

Acceptance date: 08/02/2015

ISSN (print): 1522-1946

ISSN (electronic): 1522-726X

Publisher: Wiley-Blackwell Publishing, Inc.


DOI: 10.1002/ccd.25896


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Funder referenceFunder name
MC_PC_13042Medical Research Council
MR/K006665/1Medical Research Council