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Can we influence the epidemiology of dementia? Perspectives from population-based studies

Lookup NU author(s): Professor Bloss Stephan, Professor Dame Louise Robinson


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The worldwide prevalence of dementia is predicted to rise significantly in the next three decades. However, these projections have not taken into account the role of modifiable risk factors and whether any prevention strategies might influence the predicted trend. Attempts at pharmacological disease modification have largely been disappointing, and the difficulties in conducting dementia trials are reviewed here. In contrast, recent population studies in high-income countries suggest that the epidemiology may be changing with a possible decline in incident dementia, or even a reduction in age-specific prevalence. Therefore, efforts to develop public health interventions may prove to be the more successful approach to addressing dementia at a societal level.

Publication metadata

Author(s): Birdi R, Stephan BCM, Robinson L, Davis D

Publication type: Review

Publication status: Published

Journal: Postgraduate Medical Journal

Year: 2015

Volume: 91

Issue: 1081

Pages: 651-654

Print publication date: 01/11/2015

Online publication date: 31/08/2015

Acceptance date: 09/08/2015

ISSN (print): 0032-5473

ISSN (electronic): 1469-0756



DOI: 10.1136/postgradmedj-2015-133244