Toggle Main Menu Toggle Search

Open Access padlockePrints

A surgical approach in the treatment of preputial gland abscesses in mice

Lookup NU author(s): Henri Bertrand, Dr Aurelie Thomas, Yvette Ellen, Robert Dorward, Emeritus Professor Paul FlecknellORCiD



This work is licensed under a Creative Commons Attribution 4.0 International License (CC BY 4.0).


Background: Preputial gland infection is a common occurrence in non-breeder male mice and can lead to abscesses. This report describes a surgical approach to treating and preventing this condition.Results: Surgical removal of the glands was undertaken in 258 male C3H/HeNHsd mice. The glands were successfully removed in all of the animals with a low rate of post-surgery complications. Abscess recurrence due to incomplete gland resection occurred in 2.3 % of animals. Surgical wound opening (3.1 %) and infection of the surgical site (2.3 %) also occurred but were treated successfully.Conclusion: In the study described here, early intervention was successful in preventing intercurrent infection compromising both animal welfare and the outcome of the study.

Publication metadata

Author(s): Bertrand HGMJ, Thomas AA, Ellen YC, Dorward RS, Flecknell PA

Publication type: Article

Publication status: Published

Journal: BMC Veterinary Research

Year: 2016

Volume: 12

Print publication date: 19/01/2016

Online publication date: 19/01/2016

Acceptance date: 14/01/2016

Date deposited: 27/07/2016

ISSN (electronic): 1746-6148

Publisher: BioMed Central Ltd.


DOI: 10.1186/s12917-016-0636-5


Altmetrics provided by Altmetric