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Global epidemiology of urinary tract infections

Lookup NU author(s): Dr Zafer Tandogdu


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Purpose of reviewBoth in the community and hospital setting, urinary tract infections (UTIs) are common. Initial appropriate empirical treatment requires a good knowledge of epidemiological data. In this review, the most recent global epidemiological data of UTIs have been summarized.Recent findingsCommunity-associated UTI (CAUTI) prevalence is 0.7% and the main risk factors are age, history of UTI, sexual activity and diabetes. The most common pathogen is Escherichia coli and resistance rates to common antibiotics depend very much on the geographical location. The lowest observed resistance was for fosfomycin (range: 0-2.9%), nitrofurantoin (range: 0-4.4%) and mecillinam (range: 0-4%). Healthcare-associated UTI (HAUTI) frequency among HCAIs is 12.9 (confidence interval: 10.2-16%), 19.6 and 24% in the United States, Europe and developing countries, respectively. In urology departments, the prevalence is 5.1%. Resistance to almost all antibiotics in HAUTIs is above 20% and there is a significant geographical variation. Community onset HAUTIs bacterial spectrum is similar to hospital onset HAUTIs and different from CAUTIs.SummaryIt is challenging to provide with an exact frequency of UTIs. Both CAUTI and HAUTI frequency, pathogen spectrum and resistance rates vary according to geographical setting.

Publication metadata

Author(s): Tandogdu Z, Wagenlehner FME

Publication type: Review

Publication status: Published

Journal: Current Opinion in Infectious Diseases

Year: 2016

Volume: 29

Issue: 1

Pages: 73-79

Print publication date: 01/02/2016

Acceptance date: 01/01/1900

ISSN (print): 0951-7375

ISSN (electronic): 1473-6527



DOI: 10.1097/QCO.0000000000000228