Toggle Main Menu Toggle Search

Open Access padlockePrints

The Newcastle University research output collection, currently available on ePrints, will shortly be moving to a new open repository platform, Figshare. To prepare for the data migration we have paused adding new content to ePrints, and will resume once the new repository is launched. During this time you will continue to have access to ePrints (but no new content will appear). We will share updates here when available.

Detrusor after-contraction on ambulatory urodynamics in symptomatic women

Lookup NU author(s): James Coates, Rob Pickard, Dr Michael DrinnanORCiD, Professor Christopher HardingORCiD

Downloads

Full text for this publication is not currently held within this repository. Alternative links are provided below where available.

Abstract

ObjectivesTo investigate the association between detrusor after-contraction and urodynamic parameters in a cohort of patients undergoing urodynamic studies by ambulatory monitoring.MethodsAll symptomatic adult female patients with non-neurogenic lower urinary tract dysfunction having ambulatory monitoring over the period January 1998 to January 2014 were included. Urodynamic traces were reviewed to identify detrusor after-contraction. Measured urodynamic variables were Q(max) (mL/s), V-void (mL) and P-det.Qmax (cmH(2)O). Student's unpaired t-test was used to compare the mean of the variable in the detrusor after-contraction and non-detrusor after-contraction groups.ResultsWe identified 331 women with a median age of 50years (range 16-82). Detrusor after-contraction was seen after at least one void in 122 patients giving a prevalence of 37%. A total of 167 (51%) patients had detrusor overactivity. Diagnosis of detrusor overactivity was associated with the presence of detrusor after-contraction (P<0.05). Overall, patients with detrusor after-contraction had a statistically higher mean P-det.Qmax (32 vs 28cmH(2)O, P=0.04) and lower mean voided volume (300 vs 378mL, P<0.001).ConclusionThese findings suggest a relatively high prevalence of detrusor after-contraction during ambulatory monitoring, and an association between detrusor overactivity, V-void, P-det.Qmax and detrusor after-contraction recorded during ambulatory monitoring. Therefore, a link between detrusor after-contractions and the syndrome of overactive bladder can be postulated.

Publication metadata

Author(s): Veeratterapillay R, Coates J, Leonard A, Pickard R, Drinnan M, Harding C

Publication type: Article

Publication status: Published

Journal: International Journal of Urology

Year: 2015

Volume: 22

Issue: 11

Pages: 1058-1062

Print publication date: 01/11/2015

Online publication date: 24/08/2015

Acceptance date: 26/06/2015

ISSN (print): 0919-8172

ISSN (electronic): 1442-2042

Publisher: Wiley-Blackwell

URL: http://dx.doi.org/10.1111/iju.12887

DOI: 10.1111/iju.12887

Altmetrics

Altmetrics provided by Altmetric

Share