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Coronary revascularisation in older patients with non-ST elevation acute coronary syndromes

Lookup NU author(s): Dr Hannah Sinclair, Professor Vijay KunadianORCiD


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With an ageing population, older patients with non-ST elevation acute coronary syndrome are at higher risk of adverse outcomes but are far less likely to receive invasive revascularisation, contemporary antiplatelet therapy or drug-eluting stents than their younger counterparts. Accurate risk stratification in the older age groups may aid individualised decision-making with respect to identifying which patients will benefit most from invasive revascularisation, but more research is needed in this field. Based on current knowledge in this field, it would be appropriate following risk stratification to offer optimal medical therapy plus invasive care to older patients at high risk of future cardiovascular events but at low risk of complications and to offer optimal medical therapy alone to those who are deemed low risk of future events with high risk of developing procedural complications and severely frail patients.

Publication metadata

Author(s): Sinclair H, Kunadian V

Publication type: Review

Publication status: Published

Journal: Heart

Year: 2016

Volume: 102

Issue: 6

Pages: 416-424

Print publication date: 01/03/2016

Online publication date: 06/01/2016

Acceptance date: 14/11/2015

ISSN (print): 1355-6037

ISSN (electronic): 1468-201X



DOI: 10.1136/heartjnl-2015-307859