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Lookup NU author(s): Dr Veronika Boczonadi, Professor Rita HorvathORCiD
This work is licensed under a Creative Commons Attribution 4.0 International License (CC BY 4.0).
There is increasing evidence that common molecular pathways in neurons are closely linked with mitochondrial function and that mitochondrial dysfunction is connected to various forms of neurodegenerative diseases. For instance, mitochondria are involved in amyloid- (A) deposition in Alzheimer's disease, although the exact molecular pathways remain largely unknown. Brunetti etal () in this issue of EMBO Molecular Medicine provide a novel link between A accumulation and mitochondria. A pathogenic mutation in a Norwegian family inthe mitochondrial metallopeptidase PITRM1 is found to underlie a novel mitochondrial neurodegenerative phenotype associated with A accumulation.
Author(s): Boczonadi V, Horvath R
Publication type: Editorial
Publication status: Published
Journal: EMBO Molecular Medicine
Year: 2016
Volume: 8
Issue: 3
Pages: 173-175
Print publication date: 01/03/2016
Online publication date: 26/01/2016
Acceptance date: 01/01/1900
ISSN (print): 1757-4676
ISSN (electronic): 1757-4684
Publisher: Wiley-Blackwell
URL: http://dx.doi.org/10.15252/emmm.201506050
DOI: 10.15252/emmm.201506050
