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Comparison of Bacterial Vaginosis among Pregnant Women with or without PROM (Premature Rupture of Membrane)

Lookup NU author(s): Dr Mon Mon Yee


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Borneo J. Med. Sc. (2013) 7: 9-14 Comparison of Bacterial Vaginosis among Pregnant Women with or without PROM (Premature Rupture of Membrane) Mon Mon Yee1*, Khin Mon2, Daw Khin Saw Naing3 1Department of Reproductive Health, University Malaysia Sabah, Kota Kinabalu, Sabah,Malaysia*, 2Department of Obstetrics and Gynaecology, Universitiy of Medicine 1, Yangon, Myanmar 3Department of Community & Family Medicine, University Malaysia Sabah, Kota Kinabalu, Sabah, Malaysia Bacterial vaginosis (BV) represents a complex changes in vaginal flora characterized by a reduction in concentration of the normally dominant lactobacilli and an increase in concentration of other organisms particularly the anaerobes Gardnerella vaginalis and Mycoplasm hominis. The frequency of BV among pregnant women ranges from 16% to 19%. Bacterial vaginosis was reported to be associated with premature rupture of membranes (relative risk 3.8, 95% confidence interval 1.6 to 9.0, P<0.01). The objective of the study was to determine the association between bacterial vaginosis (BV) and premature rupture of membranes (PROM) among pregnant women. A total of 120 admitted cases with PROM in the antenatal ward of Central Women’s Hospital in Yangon, Myanmar was included in the study. The pregnant mothers without PROM admitted to the same hospital within the same period served as controls. Vaginal discharge was taken for pH assessment and Amine test for fishy odour. Wet film was prepared to identify the presence of clue cells suggestive of bacterial vaginosis. Clinical composite criteria and Gram stain smear were used to diagnose bacterial vaginosis. Results showed that the prevalence of bacterial vaginosis was 32.5% in PROM and 18.3% in non-PROM cases. Preterm delivery was significantly higher (X2= 5.74, P<0.05) in BV positive group regardless of their PROM status. Puerperial infection was significantly higher in BV positive PROM group than those of BV negative PROM (X2=8.67, P<0.01). Bacterial vaginosis is significantly associated with PROM as well as poor pregnancy outcomes. Thus mandatory screening for BV in antenatal care is highly recommended.

Publication metadata

Author(s): Yee M, Mon K, Naing D

Publication type: Article

Publication status: Published

Journal: Borneo Journal of Medical Science

Year: 2013

Volume: 7

Pages: 9-14

Print publication date: 21/05/2014

Online publication date: 09/05/2013

Publisher: School of Medicine, University Malaysia Sabah