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Bridging to lung transplantation for severe pulmonary hypertension using dual central Novalung lung assist devices

Lookup NU author(s): Jonny Mayes, Professor John Dark, Stephen Clark


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This case describes the technique of using dual Novalungs (a pumpless extracorporeal system) to bridge a patient with idiopathic pulmonary hypertension to bilateral lung transplantation. A 41-year old lady with idiopathic pulmonary hypertension (with a possible veno-occlusive element) presented with symptoms of end-stage heart and lung failure. This was refractory to medical management with iloprost, sildenafil and bosentan. The patient was placed on the urgent waiting list for lung transplantation and central pulmonary artery to left atrial Novalung insertion was performed. Local anaesthetic was given before performing peripheral cardiopulmonary bypass due to the high risk of cardiac arrest. Two days later, donor organs became available and the patient was taken for double-lung transplantation. The pulmonary artery cannula was removed leaving a large defect. This was then closed using a bovine pericardial patch. Due to the damaged right superior pulmonary vein from Novalung cannulation, cardioplegia was given to facilitate an open atrial anastomosis. After 13 days in the intensive therapy unit, she was transferred to the ward. There were no further complications and she has been discharged home.

Publication metadata

Author(s): Mayes J, Niranjan G, Dark J, Clark S

Publication type: Article

Publication status: Published

Journal: Interactive Cardiovascular and Thoracic Surgery

Year: 2016

Volume: 22

Issue: 5

Pages: 677-678

Print publication date: 01/05/2016

Online publication date: 26/01/2016

Acceptance date: 09/12/2015

ISSN (print): 1569-9293

ISSN (electronic): 1569-9285

Publisher: Oxford University Press


DOI: 10.1093/icvts/ivv393


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