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Concise syntheses of bridged morpholines

Lookup NU author(s): Dr Victorovich Zaytsev, James Pickles, Dr Suzannah HarnorORCiD, Dr Alistair Henderson, Mohammed Al Yasiri, Dr Paul Waddell, Dr Celine CanoORCiD, Professor Roger Griffin, Professor Bernard Golding

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Abstract

Concise and practical syntheses of 8-oxa-3-aza-bicyclo[3.2.1]octane and 9-oxa-3-aza-bicyclo[3.3.1]nonane are described starting from furan-2,5-dicarboxylic acid and 4H-pyran-2,6-dicarboxylic acid, respectively, and using a solvent-free step for a key cyclisation.

Publication metadata

Author(s): Zaytsev AV, Pickles JE, Harnor SJ, Henderson AP, Alyasiri M, Waddell PG, Cano C, Griffin RJ, Golding BT

Publication type: Article

Publication status: Published

Journal: RSC Advances

Year: 2016

Volume: 6

Issue: 59

Pages: 53955-53957

Online publication date: 27/05/2016

Acceptance date: 25/05/2016

Date deposited: 19/08/2016

ISSN (electronic): 2046-2069

Publisher: Royal Society of Chemistry

URL: http://dx.doi.org/10.1039/c6ra08737j

DOI: 10.1039/c6ra08737j

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