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Concise syntheses of bridged morpholines

Lookup NU author(s): Dr Victorovich Zaytsev, James Pickles, Dr Suzannah HarnorORCiD, Dr Alistair Henderson, Mohammed Al Yasiri, Dr Paul Waddell, Dr Celine CanoORCiD, Professor Roger Griffin, Emeritus Professor Bernard Golding



This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License (CC BY-NC 4.0).


Concise and practical syntheses of 8-oxa-3-aza-bicyclo[3.2.1]octane and 9-oxa-3-aza-bicyclo[3.3.1]nonane are described starting from furan-2,5-dicarboxylic acid and 4H-pyran-2,6-dicarboxylic acid, respectively, and using a solvent-free step for a key cyclisation.

Publication metadata

Author(s): Zaytsev AV, Pickles JE, Harnor SJ, Henderson AP, Alyasiri M, Waddell PG, Cano C, Griffin RJ, Golding BT

Publication type: Article

Publication status: Published

Journal: RSC Advances

Year: 2016

Volume: 6

Issue: 59

Pages: 53955-53957

Online publication date: 27/05/2016

Acceptance date: 25/05/2016

Date deposited: 19/08/2016

ISSN (electronic): 2046-2069

Publisher: Royal Society of Chemistry


DOI: 10.1039/c6ra08737j


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