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A Systematic Review of the Definitions of Vascular Cognitive Impairment, No Dementia in Cohort Studies.

Lookup NU author(s): Stephanie Harrison, Dr Eugene TangORCiD, Professor John-Paul TaylorORCiD, Dr Louise Allan, Professor Dame Louise Robinson, Emerita Professor Carol Jagger, Professor Bloss Stephan



This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License (CC BY-NC 4.0).


BACKGROUND/AIMS:No set operational criteria for vascular cognitive impairment, no dementia (VCI-ND) have yet been established. The aim of this study is to undertake a systematic review to compare definitions of VCI-ND that have been used in cohort studies.METHODS:Medline, PsycINFO and Embase were searched from inception to October 13, 2015. Initially, 3,142 records were screened, and 30 were included in this review.RESULTS:No single set of criteria for defining VCI-ND was identified. VCI-ND was broadly defined as an absence of dementia, cognitive impairment in at least one cognitive domain with signs of vascular involvement, and intact activities of daily living.CONCLUSION:Defining criteria will enable individuals with VCI-ND to be efficiently compared across cohort studies to more accurately determine the prevalence and risk of dementia.

Publication metadata

Author(s): Harrison SL, Tang EY, Keage HA, Taylor JP, Allan L, Robinson L, Jagger C, Rockwood K, Stephan BC

Publication type: Article

Publication status: Published

Journal: Dementia and Geriatric Cognitive Disorders

Year: 2016

Volume: 42

Issue: 1-2

Pages: 69-79

Print publication date: 01/09/2016

Online publication date: 31/08/2016

Acceptance date: 06/07/2016

Date deposited: 10/10/2016

ISSN (print): 1420-8008

ISSN (electronic): 1421-9824

Publisher: Karger


DOI: 10.1159/000448213

PubMed id: 27578207


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